This one is way over my head, but points to different user-interfaces that break away from the WIMP-model:
By okreylos. Old video of building a nano-structure using a bimanual interface. The interaction was recorded on a “immersive workbench,” a single-screen virtual reality environment with one tracked stylus and two tracked data gloves. The video is slightly sped up by accident. The Nanotech Construction Kit is now available for download on my Research and Development page, http://idav.ucdavis.edu/~okreylos/ResDev/NanoTech/.